Individuals in populations (be they fruit flies or people) vary in gene expression. Only some of this variability contributes to differences in higher level phenotypes. Our research addresses the fundamental question of how variability in gene regulation translates to variability in complex traits.

Projects in our lab involve a variety of phenotypes including homeostatic behaviors, sexually dimorphic traits and immunity/defense. Our interests are linked by common questions related to the role of gene regulation and regulatory networks in the path from genotypes to phenotypes. More importantly, all of these traits are linked to one another via underlying genetic networks. Ultimately both the genetics of the individual traits and the connections between them are important in both basic biology (ecology and evolution), in industry (agriculture and synthetic biology) and in human health.